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王继军

王继军,男,1966年11月生,医学博士,博士生导师,上海交通大学医学院附属精神卫生中心主任医师。1989年北京医科大学临床医学系毕业后,一直从事精神障碍治疗工作。1991年-1994年在上海第二医科大学攻读硕士;2001年-2004年在日本琉球大学攻读医学博士,获得教育部“国家优秀自费留学生”称号。2009年-2010年,美国哈佛大学麻省总院精神科访问学者。自2006年起,担任上海市精神卫生中心脑电影像眼动研究室主任。目前,兼任中国科学院脑科学与智能技术卓越创新中心脑疾病客座研究员,上海市重性精神病重点实验室PI。主要学术任职有:中国神经科学学会精神病学基础与临床分会(CSNP)委员,CSNP精神病性障碍研究联盟盟主,精神医学出版物(Asian J Psychiatry、BMC Psychiatry、General Psychiatry)编委。2006年上海市浦江人才,2015年上海市优秀学术带头人。 长期从事精神疾病脑电和磁共振信号研究,开发精神障碍新型神经调控干预技术-跨颅磁刺激和超声刺激等。建立了“上海精神病高危队列(SHARP)”。牵头国家科技部“十三五重大慢性非传染性疾病防控研究”重点专项“精神分裂症分期识别生物学标记与多级风险布控体系建构(2016YFC1306800)”项目。已经完成科技部863面上项目(2008AA02Z412)和国家自然科学基金项目多项,在JAMA Psychiatry、Mol Psychiatry 和Am J Psychiatry等杂志上发表论著150篇以上。主编专著1部,参编10余部。曾获卫生部科技进步三等奖、上海市科技进步二等奖。

    主要研究方向及内容

    1.精神病性障碍临床高危人群发病风险量化评估和预测。
    2.精神病性障碍的神经电生理学和神经影像学发病机制、生物学诊断标记。
    3.精神障碍的非药物干预技术(神经调控、营养补充等)研发。

    代表性论文

    Zhang T, Xu L, Li H, Woodberry KA, Kline ER, Jiang J, Cui H, Tang Y, Tang X, Wei Y, Hui L, Lu Z, Cao L, Li C, Niznikiewicz MA, Shenton ME, Keshavan MS, Stone WS, Wang J*. Calculating individualized risk components using a mobile app-based risk calculator for clinical high risk of psychosis: findings from ShangHai At Risk for Psychosis (SHARP) program. Psychol Med. 2019 Dec 16:1-8.

    Yang Z, Wu J, Xu L, Deng Z, Tang Y, Gao J, Hu Y, Zhang Y, Qin S, Li C, Wang J*. Individualized psychiatric imaging based on inter-subject neural synchronization in movie watching. Neuroimage. 2019 Sep 27:116227. doi: 10.1016/j.neuroimage.2019.116227.

    Zhang T, Tang X, Li H, Woodberry KA, Kline ER, Xu L, Cui H, Tang Y, Wei Y, Li C, Hui L, Niznikiewicz MA, Shenton ME, Keshavan MS, Stone WS, Wang J*. Clinical subtypes that predict conversion to psychosis: A canonical correlation analysis study from the ShangHai At Risk for Psychosis program. Aust N Z J Psychiatry.  2019 Sep 5:4867419872248.

    Tang Y, Pasternak O, Kubicki M, Rathi Y, Zhang T, Wang J, Li H, Woodberry KA, Xu L, Qian Z, Zhu A, Whitfield-Gabrieli S, Keshavan MS, Niznikiewicz M, Stone WS,  McCarley RW, Shenton ME, Wang J*, Seidman LJ. Altered Cellular White Matter But Not Extracellular Free Water on Diffusion MRI in Individuals at Clinical High Risk for Psychosis. Am J Psychiatry. 2019 Oct 1;176(10):820-828.

    Zhang T, Zhu J, Xu L, Tang X, Cui H, Wei Y, Wang Y, Hu Q, Qian Z, Liu X, Tang Y, Li C, Wang J*. Add-on rTMS for the acute treatment of depressive symptoms is probably more effective in adolescents than in adults: Evidence from real-world clinical practice. Brain stimulation. 2019; 12(1):103-109.

    Wang J, Tang Y, Curtin A, Xia M, Tang X, Zhao Y, Li Y, Qian Z, Sheng J, Zhang T, Jia Y, Li C, Wang J*. ECT-induced brain plasticity correlates with positive symptom improvement in schizophrenia by voxel-based morphometry analysis of grey  matter. Brain stimulation. 2019; 12(2):319-328.

    Collin G, Seidman LJ, Keshavan MS, Stone WS, Qi Z, Zhang T, Tang Y, Li H, Anteraper SA, Niznikiewicz MA, McCarley RW, Shenton ME, Wang J*, Whitfield-Gabrieli S. Functional connectome organization predicts conversion to psychosis in clinical high-risk youth from the SHARP program. Mol Psychiatry. 2018 Nov 8. doi: 10.1038/s41380-018-0288-x. PubMed [journal] PMID: 30410064

    Zhang T, Xu L, Tang Y, Li H, Tang X, Cui H, Wei Y, Wang Y, Hu Q, Liu X, Li C, Lu  Z, McCarley RW, Seidman LJ, Wang J*. Prediction of psychosis in prodrome: development and validation of a simple, personalized risk calculator. Psychological medicine. 2018; :1-9.

    Zhang T, Li H, Tang Y, Niznikiewicz MA, Shenton ME, Keshavan MS, Stone WS, McCarley RW, Seidman LJ, Wang J*. Validating the Predictive Accuracy of the NAPLS-2 Psychosis Risk Calculator in a Clinical High-Risk Sample From the SHARP (Shanghai At Risk for Psychosis) Program. The American journal of psychiatry. 2018; 175(9):906-908.

    Zhang T, Xu L, Tang Y, Cui H, Wei Y, Wang J, Tang X, Li C, Wang J*. Duration of untreated prodromal symptoms in a Chinese sample at a high risk for psychosis: demographic, clinical, and outcome. Psychological medicine. 2018; 48(8):1274-1281.

    Goff DC, Zeng B, Ardekani BA, Diminich ED, Tang Y, Fan X, Galatzer-Levy I, Li C, Troxel AB, Wang J*. Association of Hippocampal Atrophy With Duration of Untreated Psychosis and Molecular Biomarkers During Initial Antipsychotic Treatment of First-Episode Psychosis. JAMA psychiatry. 2018; 75(4):370-378.

    Zhang T, Xu L, Tang Y, Cui H, Li H, Wei Y, Xu Y, Jiang L, Zhu Y, Li C, Jiang K, Xiao Z, Wang J*. Using 'WeChat' online social networking in a real-world needs analysis of family members of youths at clinical high risk of psychosis. The Australian and New Zealand journal of psychiatry. 2018; 52(4):375-382.

    王继军。精神障碍的物理治疗。人民卫生出版社,2012.

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